Gene expression system

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4351723, 43525231, 4353201, 536 237, 536 2372, 536 241, C12P 2100, C12N 1575, C12N 121, C07H 2104

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058437029

ABSTRACT:
The present invention relates to an expression system which comprises a phage-like bacteriocin("phibacin") or a mutant thereof, or a gene or mutant of a phibacin having a function in gene expression, such as a repressor gene, which is used to transform bacterial host for the producion of proteins, in particular in gram positive bacteria.

REFERENCES:
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Buxton (1976) J. Virol. vol. 20(1): 22-28.
Yudkin et al. (1989) J. Gen. Microbio. vol. 135: 767-775.
Moran et al. (1982) Mol. Gen. Genet. vol. 186: 339-346.
Heather Wood et al., Gene, vol. 96, pp. 83-88 (1990).
Wood et al., J. Bacteriology, vol. 172, No. 5, pp. 2667-2674 (1990).
Anderson et al., J. Virology, vol. 54, No. 3, pp. 773-780 (1985).
Piggot et al., J. Gen. Microbiology, vol. 128, pp. 663-669 (1982).
Ward et al., J. gen. Microbiology, vol. 128, p. 1171-1178 (1982).
Anderson et al., J. Bacteriology, vol. 150, No. 3, pp. 1280-1286 (1982).
R. S. Buxton, J. Gen. Virol., vol. 46, pp. 427-437 (1980).

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