Gene expression regulatory DNA

Details Gene expression regulatory DNA Gene expression regulatory DNA

1996-06-03

1997-12-23

Vogel, Nancy T.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4351723, 43525232, C12P 2106, C12N 1509, C12N 121

Patent

active

057006610

ABSTRACT:
The present invention provides a gene expression regulatory DNA and a process for preparing a protein using the same.
A DNA derived from the isocitrate lyase (ICL) gene of a coryneform bacterium regulates expression of a structural gene encoding a protein when incorporated into a vector DNA together with said structural gene and introduced into a host coryneform bacterium, and a useful protein can be efficiently produced using the DNA.

REFERENCES:
patent: 4965197 (1990-10-01), Liebl et al.
patent: 5439822 (1995-08-01), Katsumata
Cadenas et al., Gene 98:117-121 (1991).
Eikmanns et al., Gene 102:93-98 (1991).
Tsuchiya et al., Bio/Technology 6:428-430 (1988).
Chung et al. "Glyoxylate Bypass Operon of Escherichia coli: Cloning and Determination of the Functional Map", J. Bacteriol. 170: 386-392, 1988.
Matsuoka, et al., "Isolation Hyperexpression, and sequencing of the aceA Gene Encoding Isocitrate Lyase in Escherichia coli", J. of Bacteriology 170: 4528-4536, 1988.

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