Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2001-07-02
2010-02-23
Kim, Young J (Department: 1637)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S007200, C435S007230, C435S091100, C435S091200
Reexamination Certificate
active
07666586
ABSTRACT:
The present invention relates to a method of determining the presence or absence of a biological condition in animal tissue, wherein the expression of genes in normal tissue and tissue from the biological condition is examined and correlated to standards. The invention further relates to the treatment of the biological condition and an assay for determining the condition. More particularly the invention concerns gene expression in epithelial tissue, such as urianry bladder under both normal and abnormal conditions.
REFERENCES:
patent: 4769330 (1988-09-01), Paoletti
patent: 5155020 (1992-10-01), Paoletti
patent: 5204243 (1993-04-01), Paoletti
patent: 5225336 (1993-07-01), Paoletti
patent: 5252348 (1993-10-01), Schreier et al.
patent: 6335170 (2002-01-01), Orntoft
patent: WO 95/21944 (1995-08-01), None
patent: WO 96/30389 (1996-10-01), None
patent: WO 97/10365 (1997-03-01), None
patent: WO 98/53319 (1998-11-01), None
patent: WO 99/51772 (1999-10-01), None
patent: WO 00/52204 (2000-09-01), None
Sanchez-Carbayo, M. Use of High-Throughput DNA Microarrays to Identify Biomarkers for Bladder Cancer, Clinical Chemistry 49(1):23-31, 2003.
H61361 from Unigene.
U90268 from Unigene.
Torben F. Orntoft, et al, “Molecular Alterations in Bladder Cancer”, Invited Editorial. Irol. Res. (1998) 26, pp. 223-233.
Marc O. Grimm, et al. “Expression and Progression Pattern of Transitional Cell Carcinoma of the Bladder”, The Journal of Urology, vol. 163, No. 4, May 2000, p. 127.
Bergkvist A. et al., “Classification of bladder tumours based on the cellular pattern. Preliminary report of a clinical-pathological study of 300 cases with a minimum follow-up of eight years,”Acta Chir Scand1965, 130(4):371-8.
Dubensky T.W. et al., “Direct transfection of viral and plasmid DNA into the liver or spleen of mice,”Proc. Natl. Acad. Sci. 1984, USA 81: pp. 7529-7533.
Kaneda Y. et al., “Increased expression of DNA cointroduced with nuclear protein in adult rat liver,”Science1989, 243:375-378.
Hiebert S.W. et al., “E1 A-dependent trans-activation of the humanMYCpromoter is mediated by the E2F factor,”Proc. Natl. Acad. Sci. 1989, USA 86: pp. 3594-3598.
Hatzoglou M. et al., “Hepatic gene transfer in animals using retroviruses containing the promoter from the gene for phosphoenolpyruvate carboxykinase,”J. Biol. Chem. 1990, 265: pp. 17285-17293.
Ferry N. et al., “Retroviral-mediated gene transfer into hepatocytes in vivo,”Proc. Natl. Acad. Sci. 1991, USA 88: pp. 8377-8381.
Schreier H. et al., “(Patho)physiologic pathways to drug targeting: artificial viral envelopes,”J. Mol. Recognit., 1995, 8:59-62.
Schreier H. et al., “Targeting of lipsomes to cells expressing CD4 using glycosylphosphatidylinositol-anchored gp120. Influence of lipsome composition on inreacellular trafficking,”J. Biol. Chem., 1994, 269: pp. 9090-9098.
Schreier H. “The new frontier: gene and oligonucleotide therapy,”Pharm. Acta Helv. 1994, 68: pp. 145-159.
Chander R. and Schreier, H., “Artificial viral envelopes containing recombinant human immunodeficiency virus (HIV) gp160,”Life Sci., 1992, 50: pp. 481-489.
Stecenko, A. A. et al., “Fusion of artificial viral envelopes containing respiratory syncytial virus (RSV) attachment (G) and fusion (F) glycoproteins with Hep-2-cells,”Pharm. Pharmacol. Lett. 1:127-129 (1992).
Sizemore D. R., et al, “AttenuatedShigellaas a DNA delivery vehicle for DNA-mediated immunization,”Science1995, 270:299302.
Zhu, H. et al., “Cellular gene expression altered by human cytomegalovirus: Global monitoring with oligonucleotide arrays,”Proc. Natl Acad USA1998, 95: 14470-75.
Morrison TB, et al. “Quantification of low-copy transcripts by continuous SYBR Green I monitoring during amplification,”Biotechniques1998, 24 (6):954-962.
Demtröder Karin
Thykjaer Thomas
Ørntoft Torben F.
Aros Applied Biotechnology APS
Edwards Angell Palmer & & Dodge LLP
Kim Young J
Williams Kathleen
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