Gene encoding transglutaminase derived from fish

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease

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4353201, 435183, 435 691, 43525233, 43525421, 43525411, 43525231, 536 232, C12N 910, C12N 510, C12N 1554, C12N 1563

Patent

active

056078498

ABSTRACT:
The present invention relates to a DNA fragment having a gene derived from fish which codes for a polypeptide possessing transglutaminase activity, a recombinant plasmid comprising a fish-derived DNA fragment which codes for a transglutaminase, a transformant into which a recombinant plasmid comprising a fish-derived DNA fragment which codes for a transglutaminase is introduced, and a method for the production of a transglutaminase, comprising culturing a transformant containing a fish-derived DNA fragment which codes for a transglutaminase.

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Phillips et al. "Genomic Structure of Keratinocyte Transglutaminase", The Journal of Biological Chemistry, vol. 257, No. 4, pp. 2282-2286 Feb. 5, 1992.
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Wood et al. "Base Composition-Independent Hybridization in Tetramethylammonium Chloride: A Method for Oligonucleotide Screening of Highly Complex Gene Libraries", Proceedings of the National Academy of Sciences USA, vol. 82, pp. 1585-1588 Mar. 1985.
Lathe "Synthetic Oligonucleotide Probes Deduced from Amino Acid Sequence Data", Journal of Molecular Biology, vol. 183, pp. 1-12 1985.
Gentile et al. "Isolation and Characterization of cDNA Clones to Mouse Macrophage and Human Endothelial Cell Tissue Transglutaminases", The Journal of Biological Chemistry, vol. 266, No. 1, pp. 478-483 Jan. 5, 1991.
Nakanishi et al. "Cloning and Sequence Analysis of cDNA Clones for Bovine Aortic-Endothelial-Cell Transglutaminase", European Journal of Biochemistry, vol. 202, pp. 15-21 1991.

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