Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...
Reexamination Certificate
2005-04-12
2005-04-12
Kerr, Kathleen (Department: 1652)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing alpha or beta amino acid or substituted amino acid...
C435S252300, C536S023100, C536S023200, C536S023700
Reexamination Certificate
active
06878533
ABSTRACT:
AnEscherichia coilmutant strain deficient in dihydrodipicolinate synthase or dihydrodipicolinate reductase is transformed by using a chromosome gene library ofBacillus methanolicus,a transformant strain which can grow on a minimal medium is selected, and recombinant DNA containing DNA which codes for dihydrodipicolinate synthase or dihydrodipicolinate reductase is obtained from the transformant.
REFERENCES:
patent: 4346170 (1982-08-01), Sano et al.
patent: 5426052 (1995-06-01), Flickinger et al.
patent: 6110713 (2000-08-01), Hanson et al.
patent: 0 841 395 (1998-05-01), None
patent: 92-8382 (1992-09-01), None
patent: WO 9640934 (1996-12-01), None
patent: 9920783 (1999-04-01), None
GenBank Accession No. L08471.Bacillus subtilisprotease, 3′ end, dipicolinate synthase subunits A and B, aspartate semialdehyde dehydrogenase, aspartokinase, dihydrodipicolinate synthase (dapA) genes (1993).*
Shevchenko et al. Expression of the genes for lysine biosynthesis ofBacillus subtilisinEscherichia coli. Tsitol Genet. (1984) 18(1): 58-60.*
J. Bouvier, et al., The Journal of Biological Chemistry, vol. 259, No. 23, pp. 14829-14834, “Nucleotide Sequence and Expression of theEscherichia coliDAPB Gene”, Dec. 10, 1984.
B. Dauce-Le Reverend, et al., European Journal of Applied Microbiology and Biotechnology, vol. 15, pp. 227-231, “Improvement ofEscherichia coliStrains Overproducing Lysine Using Recombinant DNA Techiques”, 1982.
A. Pisabarra, et al., Journal of Bacteriology, vol. 175, No. 9, pp. 2743-2749, “A Cluster of Three Genes (dapA, orf2, and dapB) Ofbrevibacterium Lactofermentum Encodes Dihydrodipicolinate Synthase, Dihydrodipicolinate Reductase, and a Third Polypeptide of Unknown Function”, May 1993.
GenBank Accession No. E46665. dihydrodipicolinate synthase (EC 4.2.1.52) dapA[similarity]—Bacillus subtilis. Created May 3, 1994.
L. Eggeling, et al., Applied Microbiology and Biotechnology, vol. 49, No. 1, pp. 24-30, “Improved L-Lysine Yield with Corynebacterium Glutamicum: Use of Dapa Resulting in Increased Flux Combined with Growth Limitation”, 1998.
D. A. Mills, et al., Applied and Environmental Microbiology, vol. 59, No. 9, pp. 2927-2937, “Cloning and Sequence Analysis of the Meso-Diaminopimelate Decarboxylase Gene FromBacillus MethanolicusMGA3 and Comparison to Other Decarboxylase Genes” Sep. 1993.
F.J. Shendel, et al., Applied and Environmental Microbiology, vol. 58, No. 9, pp. 2806-2814, “Cloning Nd Nucleotide Sequence of Gene Coding for Aspartokinase II From A Thermophilic MethylotrophicBacillusSP” Sep. 1992.
G. H. Lee, et al., Biotechnology and Bioengineering, vol. 49, pp. 639-653, “Lysine Production from Methanol at 50° C. UsingBacillus methanolicusModeling Volume Control, Lysine Concentration, and Productivity Using a Three-Phase Continuous Simulation”, Oct. 4, 1996.
N.Y. Chen, et al., Database Swal ‘Online’, ACQ04796, pp. 1-2, “Dihydrodipicolinate Synthase (EC 4.2.1.52) (DHDPS)(Vegetative Protein 81)” Oct. 1, 1993.
A. V. Sorokin, et al., Database Swal ‘Online’, AC P42976, 1 Page, “Dihydrodipicolinate Reductase (EC 1.3.1.26) (DHPR)”, Nov. 1, 1995.
Kawahara Yoshio
Sugimoto Shinichi
Tsujimoto Nobuharu
Yasueda Hisashi
Ajinomoto Co. Inc.
Cermak Shelly Guest
Kerr Kathleen
LandOfFree
Gene encoding dihydrodipicolinate synthase from Bacillus... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Gene encoding dihydrodipicolinate synthase from Bacillus..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Gene encoding dihydrodipicolinate synthase from Bacillus... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3379416