Gene encoding cationic amino acid transporter protein

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,...

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4241431, 4241521, 5303871, 5303881, 53038822, 935 15, C07H 2104, C07K 1628, A61K 39395, G01N 3353

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active

058661239

ABSTRACT:
The present invention provides a novel gene encoding a cationic amino acid transporter protein. The present invention also provides antibodies specific for the cationic amino acid transporter protein. Further, the present invention provides methods of treating a disease characterized by undesirable levels of nitric oxide and methods of inhibiting cationic amino acid transport.

REFERENCES:
patent: 5171850 (1992-12-01), Filmus et al.
Closs et al., Journal of Biological Chemistry, vol. 268(10): 7538-7544, "Identification of a Low Affinity, High Capacity Transporter of Cationic Amino Acids in Mouse Liver" (Apr. 5, 1993).
Kim et al., Nature vol. 352:725-728, (1991).

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