Gene encoding a nematode-active toxin cloned from a Bacillus thu

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

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4352528, 4353201, 4351723, 530350, 536 232, 424 93A, C12N 120, C12N 1500, A01N 6300

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052368432

ABSTRACT:
A novel B.t. gene encoding a toxin which is toxic to nematodes has been cloned from a B. thuringiensis microbe. The DNA encoding the B.t. toxin can be used to transform various prokaryotic and eukaryotic microbes to express the B.t. toxin. These recombinant microbes can be used to control nematodes in various environments.

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Aronson et al., Microbiological Reviews, vol. 50, No. 1, Mar. 1986, pp. 1-24.
Honigman et al., Gene, vol. 42, 1986, pp. 69-77.
Prichard, R. K., C. A. Hall, J. D. Kelly, C. A. Martin, A. D. Donald (1980) "The Problem of Anthelmintic Resistance in Nematodes," Australian Veterinary Journal 56:239-251.
Coles, G. C. (1986) "Anthelmintic Resistance in Sheep", Veterinary Clinics of North America: Food Animal Practice 2(2): 423-432.
Bottjer, K. P., L. W. Bone, S. S. Gill (1985) "Nematoda: Susceptibility of the Egg to Bacillus thuringiensis Toxins," Invertebrate Parasitology 60: 239-244.
Ignoffo, C. M., V. H. Dropkin (1977) "Deleterious Effects of the Thermostable Toxin of Bacillus thuringiensis on Species of Soil-Inhabiting, Myceliophagous, and Plant-Parasitic Nematodes," J. Kansas Entomological Society 50(3): 394-398.
Ciordia, H., W. E. Bizzell (1961) "A Preliminary Report on the Effects of Bacillus thuringiensis var. thuringiensis Berliner on the Development of the Free-Living Stages of Some Cattle Nematodes," J. Parasitology 47:41 (abstract).

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