Gene encoding a DNA repair enzyme and methods of use thereof

Details Gene encoding a DNA repair enzyme and methods of use thereof Gene encoding a DNA repair enzyme and methods of use thereof

2009-01-16

2010-11-09

Harris, Alana M (Department: 1643)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C436S086000, C514S001000, C514S002600, C514S008100, C514S012200, C435S004000, C435S007100, C435S007400, C435S007920, C435S007930

Reexamination Certificate

active

07829671

ABSTRACT:
An isolated nucleic acid molecule encoding a human DNA repair enzyme, MED1, is disclosed. Like other mismatch repair genes which are mutated in certain cancers, MED1, encoding nucleic acids, proteins and antibodies thereto may be used to advantage in genetic or cancer screening assays. MED1, which recognizes and cleaves DNA, may also be used for the diagnostic detection of mutations and genetic variants.

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