Gene delivery instrument with replaceable cartridges

Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses

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4352851, 4352852, 4352853, 935 52, 935 85, C12N 510, C12M 100

Patent

active

055061257

ABSTRACT:
An apparatus for acceleration of carrier particles into a target organism which may be used for rapid, sequential particle acceleration procedures comprises a holder for removable mounting cartridges. A first removable mounting cartridge detachably holds a carrier sheet coated with carrier particles which have themselves been coated with biological material. A second removable mounting cartridge comprises a retaining screen. The mounting cartridges may be inserted into the holder before particle acceleration and replaced quickly afterwards, thereby readying the apparatus for another particle acceleration. Convenient replacement of these consumable items eliminates the need to disassemble the apparatus between each particle acceleration procedure.

REFERENCES:
patent: 3788484 (1974-01-01), Godin
patent: 3856277 (1974-12-01), Tiramani
patent: 4376053 (1983-03-01), Bullock et al.
patent: 4945050 (1990-07-01), Sanford et al.
patent: 5015580 (1991-05-01), Christou et al.
patent: 5120657 (1992-06-01), McCabe et al.
patent: 5141020 (1992-08-01), Sunderhaus et al.
patent: 5149655 (1992-09-01), McCabe et al.
patent: 5204253 (1993-04-01), Sanford et al.
Finer, et al., "Development of the particle inflow gun for DNA delivery to plant cells," Plant Cell Reports, 11:323-328 (1992).
Iida, A., et al., "Gene delivery into cultured plant cells by DNA-coated gold particles accelerated by a pneumatic particle gun," Theor. Appl. Genet. 80:813-816 (1990).
Oard, et al., "Transient Gene Expression in Maize, Rice, and Wheat Cells Using an Airgun Apparatus," Plant Physiol., 92:334-339 (1990).
Takeuchi, et al., "Plant transformation: a simple particle bombardment device based on flowing helium," Plant Molecular Biology 18:835-839 (1992).
Johnston, S. A. "Biolistic Transformation, Microbes to Mice," Nature 346:776-777 (1990).
Sanford, John C., "The biolistic process," Tibtech vol. 6 (1988).
Sanford, et al., "Delivery of Substances into Cells and Tissues Using a Particle Bombardment Process," Particulate Science and Technology 5:27-37 (1987).

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