Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1997-12-15
2000-07-18
Chambers, Jasemine
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
435440, 435455, 536 235, A61K 4800, C12N 1563, C12N 1500, C07H 2104
Patent
active
060907908
ABSTRACT:
Direct gene transfer of genetic material into an external or internal target cell site ("microseeding"), in optional combination with a wound treatment chamber, are particularly effective as a means of obtaining long term expression of native or non-native polypeptides in a host. A wide variety of proteins and materials can be expressed, either for secretion into the general blood and lymphatic system, or to alter the properties of the protein, for example, to not express proteins eliciting an immune response. The use of the optional wound chamber system for gene transfer to skin target sites also allows non-invasive assessment of the success of transfer by assaying for the presence of the expressed protein in wound fluid, in contrast to the prior art use of invasive techniques, such as biopsies, in order to achieve the same assessment of early expression.
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Baker Anne-Marie
Chambers Jasemine
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