Gene coding for glucose-6-phosphate-dehydrogenase proteins

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

Reexamination Certificate

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Details

C435S115000, C435S189000, C435S320100, C435S252300, C435S348000, C435S325000, C435S254100, C536S023100

Reexamination Certificate

active

10495291

ABSTRACT:
The present invention relates to isolated nucleic acid molecules encoding mutants of glucose-6-phosphate dehydrogenase, and vectors and hosts cells including such nucleic acid molecules. These nucleic acid molecules are involved in the biosynthesis of a fine chemical, e.g., an amino acid such as lysine. The present invention also relates to methods of producing and modulating the production of fine chemicals, e.g., lysine, by culturing recombinant microorganisms containing these nucleic acid molecules under conditions such that the fine chemical is produced.

REFERENCES:
patent: WO 01/00844 (2001-01-01), None
patent: WO 01/04322 (2001-01-01), None
patent: 1108790 (2001-06-01), None
patent: WO 01/70995 (2001-09-01), None
patent: WO 01/98472 (2001-12-01), None
patent: WO 2005/075631 (2005-08-01), None
Kalinowski J. et al. The completeCorynebacterium glutamicumATCC13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins, J. Biotechnol. 2003, 104, 5-25.
Moritz et al. “Kinetic properties of the glucose-6-phosphate and 6-phosphogluconate dehydrogenases fromCorynebacterium glutamicumand their application for predicting pentose phosphate pathway fluxin vivo.” Eur J Biochem. Jun. 2000;267(12):3442-52.
Bathe, Brigitte et al, “A physical and genetic map of theCorynebacterium glutamicumATCC 13032 chromosome,”Mol. Gen. Genet., vol. 252(3):255-265 (1996).
Cole, S.T. et al, “Deciphering the biology ofMycobacterium tuberculosisfrom the complete genome sequence,”Nature, vol. 393(6685):537-544 (1998).
Database EMBL: Sequence (Online) Accession No. 006814. “6-phosphogluconolactolase (6PGL) ofMycobacterium tuberculosis,” Nov. 1, 1997.
Eikmanns, Bernhard J. et al, “The phosphoenolpyruvate carboxylase gene ofCorynebacterium glutamicum: Molecular cloning, nucleotide sequence, and expression,”Mol. Gen. Genet., vol. 218:330-339 (1989).
Peters-Wendisch, Petra G. et al, “Pyruvate carboxylase fromCorynbacterium glutamicum: characterization, expression and inactivation of thepycgene,”Microbiology, vol. 144:915-927 (1998).

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