Gene coded for interleukin-2 polypeptide, recombinant DNA carryi

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4353201, C12P 2100, C12P 2102, C12N 1500

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active

056208685

ABSTRACT:
A gene coded for a polypeptide which possesses interleukin-2 is isolated, and connected with a vector DNA which is capable of replicating in a procaryotic or eucaryotic cell at a position downstream of a promoter gene in the vector obtaining a recombinant DNA, with which the cell is transformed to produce interleukin-2.

REFERENCES:
patent: 4443539 (1984-04-01), Fraser et al.
patent: 4738927 (1988-04-01), Taniguchi et al.
Gray et al; Nature 295: 503 (1982).
Nagata et al; Nature 284:316 (1980).
Pavlakis et al; Proc. Natl. Acad. Sci. USA 78: 7398 (1981).
Hitzeman et al; Nature 293: 717 (1981).

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