Gene chip technology for determining memory genes

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S091100, C435S283100, C435S287200, C536S023100, C536S024310

Reexamination Certificate

active

07005256

ABSTRACT:
The present invention relates to methods of identifying genes involved in memory formation. This is accomplished by performing a gene chip identification of those genes expressed during transcription-dependent memory formation but not during transcription-independent memory formation. A statistical analysis of the gene chip identification output yields a set of genes that are involved in transcription-dependent memory formation.

REFERENCES:
patent: 5143854 (1992-09-01), Pirrung et al.
patent: 5405783 (1995-04-01), Pirrung et al.
patent: 5445934 (1995-08-01), Fodor et al.
patent: 5527681 (1996-06-01), Holmes
patent: 5837832 (1998-11-01), Chee et al.
patent: 5929223 (1999-07-01), Tully et al.
patent: 6040138 (2000-03-01), Lockhart et al.
patent: 6045996 (2000-04-01), Cronin et al.
patent: 6051559 (2000-04-01), Tully et al.
patent: WO 90/15070 (1990-12-01), None
patent: WO 92/10092 (1992-06-01), None
patent: WO 92/10588 (1992-06-01), None
patent: WO 95/11995 (1995-05-01), None
patent: WO 96/11270 (1996-04-01), None
Luo et al. “Hippocampal gene expresion analysis of young and aged rats in complex maze learning by cDNA microarray” Society for Neuroscience Abstracts, 1999, 25(1-2):2164.
Dubnau, J. and Tully, T., “Gene Discovery in Drosophila: New Insights for Learning and Memory”,Annu Rev Neurosci, 21:407-444 (1998).
Yin, J.C.P., et al., “Induction of a Dominant Negative CREB Transgene Specifically Blocks Long-Term Memory in Drosophila”,Cell, 79:49-58 (1994).
Yin, J.C.P., et al., “CREB as a Memory Modulator: Induced Expression of a dCREB2 Activator Isoform Enhances Long-Term Memory in Drosophila”,Cell, 81:107-115 (1995).
Josselyn, S.A., et al., “Overexpression of CREB in the Amygdala Facilitates the Formation of Long-Term Memory Measured with Fear Potentiated Startle in Rats”,Society for Neuroscience, vol. 24, p. 926, Abstract 365.10 (1998).
Kogan, J.H., et al., “Spaced training induces normal long-term memory in CREB mutant mice”,Current Biology, 7:1-11 (1996).
Bartsch, D., et al., “Aplysia CREB2 Represses Long-Term Facilitation: Relief of Repression Converts Transient Facilitation into Long-Term Functional and Structural Change”,Cell, 83:979-992 (1995).
Bourtchuladze, R., et al., “Deficient Long-Term Memory in Mice with a Targeted Mutation of the cAMP-Responsive Element-Binding Protein”,Cell, 79:59-68 (1994).
Tully, T., et al., “Genetic Dissection of Consolidated Memory in Drosophila”,Cell, 79;35-47 (1994).
Ramsay, G., “DNA chips: State-of-the-art”,Nature Biotechnology, 16:40-44 (1998).
Cavallaro, S. et al., “Late memory-related genes in the hippocampus revealed by RNA fingerprinting,”Proc. Natl. Acad. Sci., USA, 94:9669-9673 (1997).
Bourtchouladze, R. et al., “Different Training Procedures Recruit Either One or Two Critical Periods for Contextual Memory Consolidation, Each of Which Requires Protein Synthesis and PKA,”Learning and Memory, 5(4-5) :365-374 (1998).
Pedreira, M.E. et al., “Massed and Spaced Training Build Up Different Components of Long-Term Habituation in the CrabChasmagnathus,” Animal Learning and Behaviour, 26(1) :34-45 (1998).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Gene chip technology for determining memory genes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Gene chip technology for determining memory genes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Gene chip technology for determining memory genes will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3643668

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.