Gene and protein applicable to the preparation of vaccines for r

Details Gene and protein applicable to the preparation of vaccines for r Gene and protein applicable to the preparation of vaccines for r

1993-12-20

1998-07-21

Housel, James C.

Chemistry: molecular biology and microbiology

Vector, per se

4241841, 4241851, 4242341, 4352523, 530350, 536 231, 536 237, C12N 1500, C12N 120, A61K 3900, C07H 2102

Patent

active

057834415

ABSTRACT:
All or part of the DNA sequence of the gene which encodes the S-layer protein of R. prowazekii as illustrated in Sequence ID No. 1 as well as a truncated identical piece of this gene in R. typhi as well as the 5' and 3' noncoding regions can be used for vaccination against typhus and spotted fever rickettsial infection or to diagnose the diseases caused by these bacteria. The invention is also accomplished by the deduced amino acid sequence of the S-layer protein of R. prowazekii derived from the DNA sequence of the encoding gene. Further, the invention includes the peptide or protein products based on all or parts of this gene.

REFERENCES:
Gilmore, R.D. et al. Mol. Macrobio. 3(11) : 1575-1586 (1989).
Lee, C. C. et al. Science 239 : 1288-1291 (1988).
McDonald, G. et al. Science 235 : 83-85 (1987).
Krause, D.C. et al. Infect Imimun. 47(1) : 157-165 (1985).
Raonlt, D. et al. J. Immunol. Meth. 125:57-65 (1989).
Ellis, R.W. "New Technologies for Making Vaccines" In Vaccines Plotkin & timer Eds., W.S. Saunders Co. (1988) pp. 568-575.
Boslego, J.W. et al. "Gonorrhea Vaccines" In Vaccines & Immunotherapy S.J. Cryz Ed., Pergrmon Press (1991) pp. 211-222.
Aniskovich, L.P. et al. Acta, Virol 35 :90-102 (1991)
Ching, W.M. et al. Ann. N.Y. Acad. Sci. 590: 334-351 (1990).

Affiliated with

Also associated with

Rating

Gene and protein applicable to the preparation of vaccines for r does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Gene and protein applicable to the preparation of vaccines for r, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Gene and protein applicable to the preparation of vaccines for r will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1646235