Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1995-04-27
1997-07-01
Allen, Marianne P.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
530402, C07K 14315
Patent
active
056440308
ABSTRACT:
The subject invention concerns novel polynucleotide sequences which code for polypeptides which bind IgA. A further aspect of the invention are hybrid proteins (and genes encoding these hybrid proteins) which comprise binding domains for both IgA and IgG.
REFERENCES:
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Lindahl, G. et al. (1990) "Characterization of an IgA Receptor from Group B Streptococci: Specificity for serum IgA" Eur. J. Immunol. 20:2241-2247.
Heden, L. et al. (1991) "Molecular characterization of an IgA receptor from group B streptococci: Sequence of the gene, identification of a proline-rich region with unique structure and isolation of N-terminal fragments with IgA-binding capacity" Eur. J. Immuol. 21:1481-1490, (sequence only).
Allen Marianne P.
Brown Karen E.
Medical College of Ohio
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