Gene 763 of phytopathogenic fungus Magnaporthe grisea and...

Details Gene 763 of phytopathogenic fungus Magnaporthe grisea and... Gene 763 of phytopathogenic fungus Magnaporthe grisea and...

2006-07-04

2006-07-04

Wax, Robert A. (Department: 1653)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

C435S254110, C435S320100, C435S325000, C536S023500

Reexamination Certificate

active

07070981

ABSTRACT:
The invention concerns a novel nucleic acid fragment of the genome of rice pathogenic fungusMagnaporthe griseacomprising a gene coding for a protein (hereafter referred to as gene 763) whereof the presence and integrity are indispensable for pathogenesis of said fungus with respect to rice and barley. The invention also concerns the promoter of said gene, the gene coding for protein 763, protein 763 and uses thereof for identifying potential biological targets for novel fungicide molecules and for isolating genes coding for proteins controlling biochemical functions essential to the pathogenesis of the fungusMagnaporthe griseawith respect to rice and barley. The invention further concerns compounds inhibiting pathogenesis of fungi related to the expression of gene 763.

REFERENCES:
patent: WO 99/13094 (1999-03-01), None
“A BAC end sequencing framework to sequence theMagnaporthe griseagenome,” XP002155631, Apr. 9, 1999.
“A BAC end sequencing framework to sequence theMagnaporthe griseagenome,” XP002155632, Mar. 15, 1999.
“Molecular characterization of meaB, a novel gene affecting nitrogen metabolite repression inAspergillus nidulans,” Polley, et al., FEBS Letters 388 (1996), pp. 200-205.
“Molecular Approaches to Antifungal Molecule Discovery,” Grosjean-Cournoyer, et al., Pesticide Chemistry and Bioscience: The Food-Environment Challenge, pp. 247-254 (1999).
“Regulatory Genes ControllingMPG1Expression and Pathogenicity in the Rice Blast FungusMagnaporthe grisea,” Lau and Hamer; The Plant Cell, vol. 8, pp. 771-781 (May 1996).

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