Geminivirus-based gene expression system

Details Geminivirus-based gene expression system Geminivirus-based gene expression system

1997-07-18

1999-11-09

Guzo, David

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435 914, 435 9142, 4353201, 435410, 435419, 435468, C12N 1583, C12N 1564, C12N 510

Patent

active

059812362

ABSTRACT:
A geminivirus based vector system for obtaining controlled expression of a nucleic acid fragment of interest is disclosed. Tissue specific regulatory regions are identified employing cDNA screening and the resulting tissue-specific regulatory regions are manipulated for use in geminivirus constructs to provide for transcription and/or expression of nucleic acid sequences nonindigenous to the geminivirus vector for introduction into plant cells. The vector system may be used to provide transformed plants having cells, tissues or parts with a modified phenotypic property.

REFERENCES:
patent: 5589379 (1996-12-01), Kridl et al.
patent: 5650303 (1997-07-01), Kridl et al.
Etessami, et al., "Mutational analysis of Complementary-Sense Gene of African Cassava Mosaic Virus DNA A," Biological Abstracts, p. Abs. 36062, (Apr. 4, 1991).
Etessami, et al., "Mutational Analysis of Complementary-sense Gene of African Cassave Mosaic Virus DNA A," Journal General Virology, vol. 72 (No. 5), p. 1005-1012.
Meyer, et al., "The Use of African Cassava Mosaic Virus as a Vector System for Plants," Gene, p. 213-217.
Sunter, et al., "Transactivation of Geminivirus AR1 and BR1 Gene Expression by the Viral AL2 Gene Product Occurs at the Level of Transcription," The Plant Cell, vol. 4 (No. 10), p. 1321-1331, (Apr. 14, 1992).
Sunter, et al., "Heterologous Complementation by Geminivirus AL2 and AL3 Genes," Virology, Academic Press, Inc., p. 203-210, (Apr. 14, 1994).
Sunter, et al., "Regulation of a Geminivirus Coat Proteiin Promoter by AL2 Protein (TrAP): Evidence for Activation and Derepression Mechanisms," Virology, 20th ed., Academic Press, p. 269-2800, (Apr. 14, 1997).
Hong, et al., "Resistance to Geminivirus Infection by Virus-Induced Expression of Dianthin in Transgenic Plants," Virology, 20th ed., Academic press, Inc., p. 119-127, (Apr. 14, 1996).
Rigden, et al., "Plant virus DNA replication processes in Agrobacterium: Insight into the origins of geminiviruses?," Proc. Natl. Acad. Sci., p. 10280-1028, (Apr. 14, 1996).
Lazarowitz, et al., "Sequence-Specific Interaction with the Viral AL1 Protein Identifies a Geminivirus DNA Replication Origin," The Plant Cell, p. 799-809 Apr. 14, 1992).
Nagar, et al., "A Geminivirus Induces Expression of a Host DNA Synthesis Protein in Terminally Differentiated Plant Cells," The Plant Cell, p. 705-719, ( Apr. 14, 1995).
Brough, et al., "Kinetics of Tomato Golden Mosaic Virus DNA Replication and Coat Protein Promoter Activity in Nicotiana tabacum Protoplasts," Virology, p. 1-9, ( Apr. 14, 1992).
Sung, et al., "Potato yellow mosaic geminivirus AC2 protein is a sequence non-specific DNA binding protein," Federation of European Biochemical Societies Letters, p. 51-54, ( Apr. 14, 1996).
Sunter, et al., "Activation and de-repression of a geminivirus (TGMC) Coat protein promoter," Abstract-ASV, p. 106, (Jul. 13, 1996).
Hidayat, et al., "complete Nucleotide Sequences of the Infectious Cloned DNAs of Bean Dwarf Mosaic Geminivirus,";0 Molecular Plant Pathology, The American Phytopathological Society, vol. 83 ( No. 2), p. 181-186, ( Apr. 14, 1993).
Groning, et al., "Simultaneous regulation of tomato golden mosaic virus coat protein and AL1 gene expression: expression of the AL4 gene may contribute to suppression of the AL1 gene," Journal of General Virology, p. 721-726, ( Apr. 14, 1994).
Hayes, et al., "Stability and expression of bacterial genes in replicating geminivirus vectors in plants," Nucleic Acids Research, IRL Press, vol. 17 ( No. 7), p. 2391-2403, (Apr. 14, 1989).
Hayes, et al., "Gene amplification and expression in plants by a replicating geminivirus vector," Letters to Nature, p. 1799-182, ( Apr. 14, 1988).
Saunders, et al., "Complementation of African cassava mosaic virus AC2 gene function in a mixed bipartite geminivirus infection," Journal of General Virology, p. 2287-2292, (Apr. 14, 1993).
Gilbertson, et al., "Pseudorecombination between infectious cloned DNA components of tomato mottle and bean dwarf mosaic geminiviruses,"Journal of General Virology, p. 23-31, (Apr. 14, 1993).
Nagar, et al., "A Geminivirus Induces Expression of a Host DNA Synthesis Protein in Terminally Differentiated Plant Cells," The Plant Cell, 1st ed., American Society of Plant Physiologists, p. 705-719, (Apr. 14, 1995).
Noris, et al., "DNA-Binding Activity of the C2 Protein of Tomato Yellow Leaf Curl Geminivirus," Virology, Academic Press, Inc., p. 607-612, ( Apr. 14, 1996).
Suarez-Lopez, et al., "DNA Replication of Wheat Dwarf Geminivirus Vectors: Effects of Origin Structure and Size," Virology, Academic Press, p. 389-399, ( Apr. 14, 1997).
Sung, et al., "Pseudorecumbination and complementation between potato yellow mosaic geminivirus and tomato golden mosaic geminivirus," Journal of General Virology, p. 2809-2815, (Apr. 14, 1995).
Sung, et al., "Mutational analysis of potato yellow mosaic geminivirus," Journal of General Virology, p. 1773-1780, ( Apr. 14, 1995).
Haley, et al., "Regulation of the Activities of African Cassava Mosaic Virus Promoters by the AC1, AC2 and AC3 Gene Products," Virology, vol. 188 (No. 2), p. 905-909.

Affiliated with

Also associated with

Rating

Geminivirus-based gene expression system does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Geminivirus-based gene expression system, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Geminivirus-based gene expression system will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1454342