Geminally substituted cyclic ether carboxylic acids, derivatives

Details Geminally substituted cyclic ether carboxylic acids, derivatives Geminally substituted cyclic ether carboxylic acids, derivatives

1987-09-02

1988-11-08

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514451, 514459, 514461, 514471, 548252, 548253, 549426, 549427, 549491, 549496, 549499, 549500, 549501, A61K 3134, A61K 3135, C07D30716, C07D30906

Patent

active

047834730

ABSTRACT:
Geminally-substituted cyclic ether carboxylic acids or derivatives thereof are provided which have the structure ##STR1## wherein Z is aryl, which may be optionally substituted with one or more of the following groups: halo, lower alkyl, lower alkoxy, hydroxy, lower alkylamino, phenyl or carbo-lower alkoxy ##STR2## R is COOH, COO alkali metal, coo lower alkyl, ##STR3## R.sup.1 is lower alkyl or aryl; n is 1 or 2;

REFERENCES:
patent: 4258058 (1981-03-01), Witte et al.
patent: 4443477 (1984-04-01), Witte et al.
Derwent 87-058524/09 (Sano 30.08.85).
Derwent 86-101869/16 (Sano 10.10.84).
Derwent 85-147824 (Meri 14.11.83).
Derwent 85-232492/38 (Fuji 12/01/84).
Derwent 85-220819/36 (Fuji 28.12.83).

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