Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-05-15
1998-03-10
Burn, Brian M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514568, 424465, 424476, A61K 3134
Patent
active
057262012
ABSTRACT:
The invention relates to oral solid pharmaceutical composition containing as active ingredient gemfibrozil and conventional pharmaceutical auxiliary agents comprising as surfactant bis-(2-ethyl-hexyl)-sodium-sulfosuccinate in an amount of 0.05-0.5% by weight relative to gemfibrozil content of the composition.
The pharmaceutical compositions according to the present invention contain a relatively small amount of a surfactant, provide uniform dissolution of the active ingredient among the different batches and the standard deviation of the dissolution rate is low.
REFERENCES:
patent: 3674836 (1972-07-01), Creger
patent: 4126637 (1978-11-01), Goel et al.
patent: 4925676 (1990-05-01), Ghebre-Sellassie et al.
patent: 4927639 (1990-05-01), Ghebre-Sellassie et al.
patent: 4971804 (1990-11-01), Ghebre-Sellassie et al.
patent: 5281421 (1994-01-01), Ghebre-Sellassie et al.
Bezzegh Denes
Drabant Sandor
Fekete Pal
Fellner, nee Kohalmi Erzsebet
Gora nee Hernyes Magdolna
Burn Brian M.
Egis Gyogyszergyar Rt.
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