Gem-dimethyl substituted bicyclic compounds useful as eukalemic

Details Gem-dimethyl substituted bicyclic compounds useful as eukalemic Gem-dimethyl substituted bicyclic compounds useful as eukalemic

1989-05-19

1990-12-25

Shen, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514255, 514869, 544405, 544406, 544407, A61K 31495, C07D24120, C07D24116

Patent

active

049803522

ABSTRACT:
Certain gem-dimethyl substituted bicyclic phenolic pyrazines of formula III possess eukalemic diuretic properties. They are of value in treating those diseases and conditions in which a eukalemic diuretic effect is required, for example in treating edema, hypertension and/or related conditions.

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Smith, R. L. et al., Diuretics--Chemistry, Pharmacology, and Medicine, "2-Aminomethylphenols: A New Class of Saluretic Agents", pp. 93-124.
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