Gelling compositions comprising optically enriched gellants

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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424 65, 514937, 514938, 514943, 514944, 554213, A61K 3120

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active

056079729

ABSTRACT:
The subject invention relates to low-aqueous gelling compositions comprising optically enriched gellants having the structure: ##STR1## wherein A and B independently represent alkyl groups such that the gellant is an asymmetric, di-chiral, di-hydroxy fatty acid that is about 90% or more in the R, R or S, S form and has from about 6 to about 30 carbon atoms.

REFERENCES:
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patent: 5362494 (1994-11-01), Zysman et al.
Tachibana et al., "Chiral Mesophases of 12-Hydroxyoctadecanoic Acid in Jelly and in the Solid State. I. A New Type of Lyotropic Mesophase in Jelly with Organic Solvents", Bull. Chem. Soc. Jpn. vol. 53, pp. 1714-1719 (1980).
Remington's Pharmaceutical Sciences, 18th ed. p. 1530.
P. Terech, "Small-angle-scattering study of 12-hydroxystearic physical organogels and lubricating greases", 269, Colloid & Polymer Science, pp. 490-500 (1991).
McGhie et al., "Conversion of (+)-ricinoleic acid into (-)-recinoleic acid", Communications to the Editor, Sep. 18, 1982, pp. 719-720, Chemistry & Industry.

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