Gelatin hard capsule enhancing the film strength

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules

Reexamination Certificate

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C424S456000

Reexamination Certificate

active

07553497

ABSTRACT:
A process for preparing gelatin hard capsule having enhanced film strength by the steps including i) adding 1˜10 wt part of PEG mixture of PEG 600 and PEG 1500 in weight ratio 40˜60:60˜40 to the solution having 100 wt part of gelatin; ii) adding 0.1˜1.2 wt part of emulsifier mixture containing acetyl glycerine fatty acid ester and sodium lauryl sulfate to the resulting mixture; and iii) allowing the obtained mixture to stand, adjusting its viscosity and forming a hard capsule therefrom. Further, this gelatin hard capsule has equal film distribution with minimum cracking or chipping when hygroscopic material is inserted.

REFERENCES:
patent: 5419916 (1995-05-01), Yamamoto et al.
patent: 6740333 (2004-05-01), Beckett et al.
patent: 1210936 (2002-06-01), None
patent: 2001170137 (2001-06-01), None

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