Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Scleroproteins – e.g. – fibroin – elastin – silk – etc.
Reexamination Certificate
2004-10-25
2009-10-20
Desai, Anand U (Department: 1656)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Scleroproteins, e.g., fibroin, elastin, silk, etc.
C514S002600, C977S773000
Reexamination Certificate
active
07605231
ABSTRACT:
The present invention relates to a gelatin derivative having an organic compound as a graft chain and a high-molecular weight micelle containing the gelatin derivative. As the organic compound, a low molecular weight compound such as succinic acid, ethylenediamine, etc., or a high-molecular weight compound such as polyethylene glycol, polylactic acid, etc. can be used. The high-molecular weight micelle can be used as a pharmaceutical composition excellent in control of sustained release or targeting property by carrying it on a drug, etc. Also, the gelatin derivative can be an excellent adhesion preventing membrane by crosslinking it.
REFERENCES:
patent: 6200590 (2001-03-01), Eley
patent: 7067144 (2006-06-01), Demopulos et al.
patent: 2003/0083389 (2003-05-01), Kao et al.
patent: 2004/0137179 (2004-07-01), Matsuda et al.
patent: 1 027 888 (2000-08-01), None
patent: 5-43453 (1993-02-01), None
patent: 8-325160 (1996-12-01), None
patent: 9-103479 (1997-04-01), None
patent: 2001-172203 (2001-06-01), None
patent: WO 98/20755 (1998-05-01), None
Kim et al., J. of Controlled Release, 1998, 51:13-22.
Kim and Byun, “Preparation and characterizations of self-assembled pegylated gelatin nanoparticles”, Biotechnol. Bioprocess Eng. 4: 210-214 (1999).
Kim and Byun, “Controlled release of All-trans-retinoic acid from pegylated gelatin nanoparticles by enzymatic degradation”, Biotechnol. Bioprocess Eng. 4: 215-218 (1999).
T. Kushibiki et al, “Gelatin to Polyethylene glycol to kara naru Bunshi Shugotai no Chosei”,Drug Delivery System, vol. 17, No. 3, p. 263 (May 10, 2002).
G. Kaul et al, “Long-Circulating Poly(Ethylene Glycol)-Modified Gelatin Nanoparticles for Intracellular Delivery”,Pharmaceutical Research, vol. 19, No. 7, pp. 1061-1067 (Jul. 2002).
J. Zimmerman et al, “Novel hydrogels as supports for in vitro cell growth: . . . ”,Biomaterials, vol. 23, No. 10, pp. 2127-2134 (May 2002).
T. Morita et al, “Preparation of gelatin micro-particles by co-lyophilization with poly(ethylene glycol): . . . ”,Intl. Journal of Pharmaceutics, vol. 219, No. 1-1, pp. 127-137 (May 2001).
PCT International Preliminary Examination Report PCT/IPEA/401 (English language translation) in the parent application PCT/JP2003/005343 (4 pages).
Sakaguchi Koji
Tabata Yasuhiko
Tanaka Shinji
Desai Anand U
Frishauf Holtz Goodman & Chick P.C.
NOF Corporation
Tabata Yasuhiko
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