Gelatin coating composition and hard gelatin capsule

Details Gelatin coating composition and hard gelatin capsule Gelatin coating composition and hard gelatin capsule

1993-07-22

1995-05-30

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424451, 424452, 424453, 424460, 424478, 424492, 514962, A61K 940, A61K 948, A61K 964

Patent

active

054199166

ABSTRACT:
There are disclosed herein a gelatin coating composition which comprises succinated gelatin as the main component and polyethylene glycol, and a hard gelatin capsule formed from said gelatin coating composition. The hard gelatin capsule has sufficient mechanical strength for filling operation. Moreover, it does not become insoluble due to reaction with a special drug having an aldehyde group filled therein. Therefore, it can be used for various drugs, especially macrolide antibiotics for which conventional hard gelatin capsules are inadequate.

REFERENCES:
patent: 4910021 (1990-03-01), Davis et al.
patent: 5209978 (1993-05-01), Kosaka et al.

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