Gelatin capsules containing a highly concentrated acetaminophen

Details Gelatin capsules containing a highly concentrated acetaminophen Gelatin capsules containing a highly concentrated acetaminophen

1994-06-22

1996-04-09

Phelan, D. Gabrielle

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424455, 424456, 424457, A61K 948

Patent

active

055059619

ABSTRACT:
A method is disclosed for increasing the solubility of acetaminophen alone or in combination with antihistamines, antitussives, decongestants, and expectorants to form a clear solution for encapsulation into a softgel. The acetaminophen is solubilized alone or in combination with the above ingredients by mixing with polyethylene glycol, propylene glycol, water, polyvinylpyrrolidone and potassium (or sodium) acetate. This invention increases the solubility of the acetaminophen to obtain the same size softgel for a 325 mg dose as is presently available for a 250 mg dose softgel product. The disclosed solvent system is useful because it provides for a highly concentrated solution of acetaminophen capable of encapsulation in a small enough capsule to permit easy swallowing.

REFERENCES:
patent: 3956490 (1976-05-01), Higuchi
patent: 5071643 (1991-12-01), Yu

Affiliated with

Also associated with

Rating

Gelatin capsules containing a highly concentrated acetaminophen does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Gelatin capsules containing a highly concentrated acetaminophen , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Gelatin capsules containing a highly concentrated acetaminophen will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-137202