Gelatin capsule dosage unit containing triamterene

Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Polymer from ethylenic monomers only

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Details

424156, 424246, 424251, 424329, A61K 948, A61K 31505, A61K 3154

Patent

active

042554136

ABSTRACT:
A gelatin capsule unit dosage form containing triamterene, 2,4,7-triamino-6-phenylpteridine, which results in rapid dissolution of the active ingredient. The dosage form comprises the addition of a combination of a surfactant and a carbonate or bicarbonate salt as diluents.

REFERENCES:
patent: 3081230 (1963-03-01), Weinstock
Ravin et al., J. of Pharm. Sci., vol. 58, 1969, pp. 1242-1245.
Stewart et al., J. Pharm. Pharmacol. vol. 31, 1979 pp. 1-6.
Newton et al., J. Pharm. Pharmacol,. vol. 26(s) pp. 30P-36P.

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