Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules
Patent
1986-10-01
1988-10-25
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Capsules
424451, 424452, 424455, A61K 948, A61K 966
Patent
active
047803169
ABSTRACT:
A pharmaceutical dosage unit form comprises one or more pharmaceutically active materials dissolved or suspended in a liquid polyethylene glycol and encapsulated in a soft gelatin capsule shell, in which the capsule shell comprises gelatin, a plasticizer therefor, and an embrittlement inhibiting composition comprising a mixture of sorbitol and at least one sorbitan. Preferably the polyethylene glycol also contains glycerin, sorbitol or propylene glycol.
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Ebert, "Soft Elastic Gelatin Capsules: A Unique Dosage Form," reprints from Pharmaceutical Technology (Oct. 1977).
R.P. Scherer Corporation
Rose Shep K.
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