Gel-like ointment containing indometacin

Details Gel-like ointment containing indometacin Gel-like ointment containing indometacin

1983-12-29

1985-09-10

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Lymphokine

514420, 514887, A61K 3140, A61K 31736

Patent

active

045405727

ABSTRACT:
In addition to indometacin, the gel-like ointment for the topical treatment of inflammation contains a water-soluble cellulose ether or/and a polyacrylic acid, the carboxyl groups of which are neutralized by a water-soluble amine, plus water and ethanol or isopropanol; the components are present in the ratio of amounts suitable for forming a gel. Determination of the level of indometacin in the serum of humans has shown that the absorption through the skin of the active compound from the new ointment is significantly higher than that from the most closely related products.

REFERENCES:
Chem. Abst. 95-103322x, (1982).
Chem. Abst. 93-13094d, (1980).

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