Gel-in-matrix containing a fractured hydrogel

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Matrices

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424422, 424443, 424464, 424484, 424488, 424500, 424501, 424935, 424529, 428289, 4283066, 4283084, 4283202, 428394, 428402, 435182, 521 28, 521 55, A61K 914, C08J 520, C12N 116

Patent

active

052779157

ABSTRACT:
A three dimensional porous matrix, such as a reticulated open-cell foam, having within its matrix structure a mechanically-fractured hydrogel containing a network of fracture channels. The mechanically-fractured hydrogel may be a gel that has been partially dewatered by compression of the gel in situ.
The porosity of the gel-in-matrix makes it useful for chromatographic applications and for immobilization of biologically-active components, where efficient, intimate contact of the hydrogel with a liquid medium is important.

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