Gel formulations containing growth factors and acrylamide polyme

Details Gel formulations containing growth factors and acrylamide polyme Gel formulations containing growth factors and acrylamide polyme

1992-11-10

1995-06-27

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

424 941, 514 21, A61K 3702, A61K 3748

Patent

active

054277787

ABSTRACT:
Gel formulations containing polypeptide growth factors having human mitogenic or angiogenic activity are provided. The gel formulations are useful for topical or incisional wound healing for cutaneous wounds, in the anterior chamber of the eye and other ophthalmic wound healing. The gel formulations also comprise a water soluble, pharmaceutically or ophthalmically compatible polymeric material for providing viscosity within various ranges determined by the application of the gel. The gel formulations provide controlled release and increased contact time of the growth factor to the wound site.

REFERENCES:
patent: 4100271 (1978-07-01), Krezanoski et al.
patent: 4717717 (1988-01-01), Finkenaur
patent: 4767628 (1988-08-01), Hutchinson et al.
patent: 4806523 (1989-02-01), Bentz et al.

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