Fabric (woven – knitted – or nonwoven textile or cloth – etc.) – Coated or impregnated woven – knit – or nonwoven fabric which... – Coated or impregnated inorganic fiber fabric
Patent
1993-08-26
1999-02-09
Bell, James J.
Fabric (woven, knitted, or nonwoven textile or cloth, etc.)
Coated or impregnated woven, knit, or nonwoven fabric which...
Coated or impregnated inorganic fiber fabric
427387, 4273898, 428429, 428447, B32B 700
Patent
active
058694099
ABSTRACT:
A gel-fiber glass (GFG) is a newly-formed sol-gel glass polymerized from tetramethoxysilane on the surface of activated glass wool fibers or activated fibrous glass. GFG is a support for trapped chemical or biochemical reagents. A thin layer of reagents trapped in gel glass during its preparation is present on the surface of a lattice of glass fibers. Columns for affinity chromatography were prepared from the GFG membranes with entrapped antigens or antibodies and were used to isolate different proteins, including tumor-associated antigens; GFG membrane demonstrated high effectiveness and stability, and can isolate proteins in extremely high amounts. The membranes can be used in diagnostic practice, generation of specific antibodies and therapy.
REFERENCES:
"Sol-Gel Science: The Physics and Chemistry of Sol-Gel Processing", Brinker et al., 1990, pp. 453, 839, 868-869.
"Doped Sol-Gel Glasses as Chemical Sensors", Rivka Zusman et al., Journal of Non-Crystalline Solids 122 (1990), pp. 107-109.
"Biochemically Active Sol-Gel Glasses: The Trapping of Enzymes", vol. 10, No. 1,2, Sep. 1990, pp. 1-5.
"Purification of Sheep Immunoglobin G Using Protein a Trapped in Sol-Gel Glass", Rivka Zusman et al., Analytical Biochemistry 201, pp. 103-106 (1992).
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