Gel composition and method for treatment of vaginal infections

Details Gel composition and method for treatment of vaginal infections Gel composition and method for treatment of vaginal infections

2005-07-05

2005-07-05

Page, Thurman K. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Biocides; animal or insect repellents or attractants

C424S400000, C424S407000, C424S484000, C424S486000, C514S405000

Reexamination Certificate

active

06913759

ABSTRACT:
A pharmaceutical composition having a gel consistency at room temperature and suitable for the treatment of a vaginal infection comprises, on a total composition weight basis, about 0.1 to about 3 weight percent of benzydamine hydrochloride, about 16 to about 35 weight percent of a polyoxyalkylene block copolymer, and about 2 to about 30 weight percent of propylene glycol, in water having a pH value in the range of about 3.5 to about 7. The weight ratio of water to polyoxyalkylene block copolymer in the composition is less than about 4:1. Optionally, the gel compositions can also contain glycerin, physiologically tolerable preservatives and buffers, as well as other pharmaceutically acceptable excipients.

REFERENCES:
patent: 5840744 (1998-11-01), Borgman
patent: WO 96/26724 (1996-09-01), None

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