Gel cassette for enhanced electrophoretic separation and process

Chemistry: electrical and wave energy – Apparatus – Coating – forming or etching by sputtering

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Details

2041828, G01N 2726, G01N 27447

Patent

active

054338379

ABSTRACT:
A gel cassette useful in electrophoretic separation of molecular fragments is disclosed, in which a gelatinous substrate is uniquely configured to concentrate similar separated fragments. Containment means is also disclosed which provides for the desired configuration of the substrate. The containment means further includes a cover design which locks into an open position to eliminate cross contamination. In addition, processes for the preparation of such cassettes and for use of the cassettes in separation and transfer apparatus are disclosed.

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patent: 4631120 (1986-12-01), Pohl
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patent: 4885697 (1989-12-01), Hubner
patent: 5087558 (1992-02-01), Webster, Jr.
patent: 5234559 (1993-08-01), Collier et al.
Anders Olsson et al. "Uniformly spaced banding pattern in DNA sequencing gels by use of field-strength gradient" Journal of Biochemical and Biophysical Methods 10 (1984) 83-90.

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