Gel bases for pharmaceutical compositions

Details Gel bases for pharmaceutical compositions Gel bases for pharmaceutical compositions

1988-10-17

1989-11-28

Schofer, Joseph L.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424456, 424434, 424464, 514944, 514941, A61K 3174, A61K 966, A61K 948

Patent

active

048836605

ABSTRACT:
Gel bases for pharmaceutical compositions comprise from about 0.5 to about 10.0% by weight ethoxylated (2 to 30 moles of ethoxylation) behenyl alcohol and from about 90 to 99.5% of a glycol solvent or from about 2.5 to about 10.0% by weight ethoxylated fatty alcohols having a chain length of from 16 to 21 carbon atoms and from 90 to about 97.5% of a glycol solvent. Preferred glycol solvents include propylene glycol and polyethylent glycols having an average molecular weight of about 200 to 800. Pharmaceutical compositions suitable for topical, transmucosal and oral administration may be prepared utilizing the novel gel bases. Methods of administration of topically, systemically and orally active pharmaceutical agents utilizing the novel gel bases are also provided.

REFERENCES:
patent: 4276430 (1981-06-01), Reller et al.
patent: 4759924 (1988-07-01), Luebbe et al.
patent: 4775678 (1988-10-01), Su et al.

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