Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 11 to 14 amino acid residues in defined sequence
Reexamination Certificate
2008-09-09
2008-09-09
Tsang, Cecilia (Department: 1654)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
11 to 14 amino acid residues in defined sequence
C514S014800, C424S085100, C424S001690
Reexamination Certificate
active
10528542
ABSTRACT:
The invention provides ligands of ganglioside GD2, including peptide ligands such as GGITNYNSALM; YCGGITNYNSACY; YCITNYNSCY; YCGGITNYNCY; YCTNYGVHCY; YCTNYGVCY; GGIANYNTS; YCGGIANYNCY; YCGGIANYNTSCY; and, YCIANYNTCY. GD2 ligands of the invention may for example be used to treat or diagnose diseases such as cancers in which cells express GD2, including neuroblastomas.
REFERENCES:
Helfand S. C., Hank J. A., Gan J., and Sondel P. M (1996) Lysis of humant tumor cell lines by canine complement plus monoclonal antiganglioside antibodies or natural canine xenoantibodies. Cellular Immunology 167: 99-107.
Cheung, N.V. et al.,Cancer Research45, pp. 2642-2649 (Jun. 1985).
Eisenberg, D. et al.,J. Mol. Biol. 179, pp. 125-142 (1984).
Gagnon, Martin et al.,Expert Opinion(2002).
Probstmeier et al.,Eur. J. Neuroscience, vol. 11, pp. 2474-2488 (1999).
Saragovi, H. Uri et al.,Nature Biotechnology, vol. 10, pp. 773-778 (Jul. 1992).
Sorkin, L.S.,Pain Medicine, vol. 1, pp. 296-302 (2000).
Gagnon Martin
Saragovi H. Uri
Audet Maury
Klarquist & Sparkman, LLP
McGill University
Tsang Cecilia
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