Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 11 to 14 amino acid residues in defined sequence
Patent
1995-03-24
1997-11-25
Budens, Robert D.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
11 to 14 amino acid residues in defined sequence
530810, 530812, 4241851, 4241931, 514 14, C07K 708, A61K 3810
Patent
active
056914474
ABSTRACT:
Disclosed are immunogens and peptides based on the binding site of gC1q-R for HIV-1 gp120, and immunogens and peptides based on the binding site of HIV-1 gp120 for gC1q-R. The sequence of the gC1q-R binding site for gp120 is shown in SEQ ID NO.: 2. The sequence of the HIV-1 gp120 binding site for gC1q-R is shown in SEQ ID NO.: 3. Also disclosed are antibodies and binding molecules to all such immunogens and peptides, and inducing the endogenous production of such antibodies.
REFERENCES:
patent: 4479934 (1984-10-01), Sedlacek et al.
patent: 4595654 (1986-06-01), Reckel et al.
Krainer et al., "Functional Expression of Cloned Human Splicing Factor SF2: Homology to RNA-Binding Proteins, U1 70K, and Drosophila Splicing Regulators," Cell 66:383-394, Jul. 26, 1991.
Honore et al., "Cloning and Expression of a cDNA Covering the Complete Coding Region of the P32 Subunit of Human Pre-mRNA Splicing Factor SF2," Gene 134:283-287, 1993.
Ghebrehiwet et al., "Isolation, cDNA Cloning, and Overexpression of a 33-kD Cell Surface Glycoprotein that Binds to the Globular Heads of C1q," J. Exp. Med. 179:1809-1821, Jun. 1994.
Geysen et al., "Use of Peptide Synthesis to Probe Viral Antigens for Epitopes to a Resolution of a Single Amino Acid," Proc. Natl. Acad. Sci. USA 81:3998-4002, Jul. 1984.
Baran Deb et al., "Molecular Cloning of Human Fibroblast Hyaluronic Acid-binding Protein Confirms Its Identity with P-32, a Protein Co-purified with Splicing Factor SF2," J. Biol. Chem. 271(4):2206-2212, Jan. 26, 1996.
Fung Michael S. C.
Kim Young Woo
Sun Bill N. C.
Sun Cecily R. Y.
Yu Liming
Budens Robert D.
Mirabel Eric P.
Tanox Biosystems, Inc.
LandOfFree
GC1q receptor, HIV-1 gp120 region binding thereto, and related p does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with GC1q receptor, HIV-1 gp120 region binding thereto, and related p, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and GC1q receptor, HIV-1 gp120 region binding thereto, and related p will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2108112