Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Patent
1988-04-22
1989-10-03
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
A61K 932
Patent
active
048715468
ABSTRACT:
Tablet formulations for the diffusable release of drugs in the gastrointestinal tract, which formulations protect the gastric mucosa from the effects of solid, gastric irritating drugs. The formulation comprises a drug tablet core, coated with a water permeable, gastrointestinal fluid insoluble polymeric coating, e.g., polymethyl methacrylate, polyethylene glycol polyvinylacetate, diethylphthalate and dioctyl sodium sulfosuccinate.
REFERENCES:
patent: 2702264 (1955-02-01), Klaui
patent: 3096248 (1963-07-01), Rudzki
patent: 3325365 (1967-06-01), Hotko et al.
patent: 4060598 (1977-11-01), Groppenbacher et al.
Feltz Dennis R.
Kornblum Saul S.
Stoopak Samuel B.
Honor Robert S.
Jewell Walter F.
Rose Shep K.
Sandoz Pharm. Corp.
Sharkin Gerald D.
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