Gastric secretion stimulation with 2-amino-5-(2-aminoethyl)-1,3,

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent

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424269, 548138, A61K 2900, A61K 3141, A61K 31415

Patent

active

042117640

ABSTRACT:
The proposed gastric secretion stimulator comprises an active principle which is 2-amino-5-(2-aminoethyl)-1,3,4-thiadiazole, and a pharmaceutical carrier for said active principle. The stimulator is used in the form of hydrochlorides. It displays a selective stimulating effect upon H.sub.2 -ceptors of secretory cells of the stomach and produces a maximum of gastric secretion, which is an important diagnostic factor. The gastric secretion stimulator of this invention is advantageous in that besides parenteral administration, it may be administered per os.

REFERENCES:
Ohta et al., J. Pharm Soc. Japan, vol. 72, 1952, pp. 1636-1639.
Ohta et al., Chem Abs., vol. 47, 1953, pp. 9323-9324.

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