Gastric cytoprotection with non-antisecretory doses of prostagla

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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424317, A61K 31215, A61K 3119

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active

040976033

ABSTRACT:
The present invention provides a method for prophylaxis of certain gastric inflammatory diseases by administration of gastric cytoprotective prostaglandins. Gastric cytoprotective prostaglandins refer to those prostaglandin-type compounds which are useful in reducing or preventing development of ulcers and other gastric lesions in the rat challenged by ingestion of ethanol, but which exhibit substantially no gastric antisecretory effects at the effective dosage for the present method.

REFERENCES:
patent: 3953495 (1976-04-01), Hayashi et al.

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