Gas-phase purification of biomolecules by ion mobility for...

Radiant energy – Ionic separation or analysis – Methods

Reexamination Certificate

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C250S283000, C250S282000

Reexamination Certificate

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07081617

ABSTRACT:
A method and device for the gas-phase separation of ionic biomolecules including peptide, and protein or inorganic cluster ions or nanoparticles by ion mobility and for depositing them intact on a surface in a spatially addressable manner is described. The surface onto which the proteins are deposited can be modified for the purpose of constructing microarrays of biologically relevant materials or for promoting the growth of highly ordered protein crystals.

REFERENCES:
patent: 6750448 (2004-06-01), Turecek et al.
patent: 6924479 (2005-08-01), Blanchard
patent: 2003/0226963 (2003-12-01), Cooks et al.
Bergmann et al, High-Molecular-Mass Multi-c-Heme Cytochromes from Mathylococcus capsulatus Bath, Feb. 1999, Journal of Bateriology, vol. 181, No. 3, p. 991-997.
Bergmann, David J. et al.; High-Molecular-Mass Multi-c-Heme Cytochromes from Methylococccus capsulatus Bath; Journal of Bacteriology, Feb. 1999, p. 991-997, vol. 181, No. 3.

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