Gas-filled microspheres with fluorine-containing shells

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Ultrasound contrast agent

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424 95, A61K 4900

Patent

active

055628931

ABSTRACT:
Improved ultrasonic imaging contrast agents are provided which are comprised of an aqueous suspension of microspheres comprising at least one gas, preferably a perfluorocarbon, encapsulated by elastic shells of a biocompatible, fluorine-containing amphiphilic material, processes for making the microspheres, and methods of diagnostic imaging using the improved contrast agents.

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