Gas driven gene delivery instrument

Surgery – Means for introducing or removing material from body for... – Treating material introduced into or removed from body...

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604 24, 604 59, 604 49, A61M 530

Patent

active

055848079

ABSTRACT:
A gas driven apparatus for accelerating particles coated with a genetic material into a target comprises a reservoir for releasably retaining a gas at a sufficiently high pressure to detach the particles from the surface of a sample cartridge and to carry the particles through the apparatus toward the target. When leaving the apparatus, the particles entrained in the gas stream pass through a substantially conical exit nozzle which causes the pattern of distribution of the particles to greatly expand. Methods for using the apparatus and for preparing the sample cartridges are also described.

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