Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2006-03-21
2006-03-21
Low, Christopher S. F. (Department: 1614)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S024300, C536S024310, C536S024320, C536S024330, C536S024500, C536S025100, C514S04400A, C435S006120, C435S377000
Reexamination Certificate
active
07015315
ABSTRACT:
Oligonucleotides and other macromolecules are provided which have increased nuclease resistance, substituent groups for increasing binding affinity to complementary strand, and subsequences of 2′-deoxy-erythro-pentofuranosyl nucleotides that activate RNase H. Such oligonucleotides and macromolecules are useful for diagnostics and other research purposes, for modulating the expression of a protein in organisms, and for the diagnosis, detection and treatment of other conditions susceptible to oligonucleotide therapeutics.
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Cook Phillip Dan
Monia Brett P.
ISIS Patent Department
ISIS Pharmaceuticals Inc.
Low Christopher S. F.
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