Gapped oligomers having site specific chiral...

Details Gapped oligomers having site specific chiral... Gapped oligomers having site specific chiral...

2005-03-15

2005-03-15

Wilson, James O. (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S024300, C536S024310, C536S024320, C536S024330, C536S025300, C536S025310, C536S026300, C536S022100

Reexamination Certificate

active

06867294

ABSTRACT:
Novel chiral compounds that mimic and/or modulate the activity of wild-type nucleic acids are disclosed. In general, the compounds are phosphorothioate oligonucleotides wherein the 5′, and the 3′-terminal internucleoside linkages are chirally Sp and internal internucleoside linkages are chirally Rp.

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