GANP protein

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C530S387900, C530S350000, C435S194000, C435S252300, C435S320100

Reexamination Certificate

active

06943237

ABSTRACT:
The object of the present invention is to provide a novel protein having a kinase activity and a gene encoding said protein. According to the present invention, there is provided a GANP protein which is represented by the amino acid sequence shown in SEQ ID No. 1 or No. 3 of the sequence listing, and is involved in the signal conversion of abnormal B cell differentiation in an autoimmune state, and has a kinase activity, and a polynucleotide which encodes said protein.

REFERENCES:
C. Thomas et al., “M17:a novel gene expressed in germinal centers”, International Immunology (1994), vol. 6, No. 8, pp. 1203-1211.
Ming-Jie Li, et al., “Rad51 expressio and localization in B cells carrying out class switch recombination”, Proc. Natl. Acad. Sci. USA (1996), vol. 93, No. 19, pp. 10222-10227.
Masaki Hikida et al., “Reexpression of RAG-1 and RAG-2 genes in activated mature mouse B cells”, Science (1996), vol. 274, No. 5295, pp. 2092-2094.
H. Shuhua, et al., “Neoteny In lymphyocytes: Rag1 and Rag2 expression in germinal center B cells”, Science (1996), vol. 274, No. 5295, pp. 2094-2097.
Kazuhiko Kuwahara et al., “Identification of a 52-kDa molecule coprecipltated with the lg receptor-related MB-1 protein that is Inducibly phosphorylated by the stimulation with phorbol myristate acetate”, J. Immunol. (1994), vol. 152, pp. 2742-2452.
Nagase et al., DNA Res., 5, 31-39, 1998.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

GANP protein does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with GANP protein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and GANP protein will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3423495

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.