Gangliosides with a modified acyl function

Details Gangliosides with a modified acyl function Gangliosides with a modified acyl function

2003-05-27

2010-12-14

Olson, Eric S (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C536S017900

Reexamination Certificate

active

07851450

ABSTRACT:
The invention relates to a ganglioside mixture, consisting of gangliosides, of the following general formula: (sugar)-OCH2—CH(—NH—CO—R1)—CH(OH)—CH═CH—R2, wherein (sugar) represents a sugar radical, the group —CO—R1represents an acyl-fatty acid which is bonded to the radical of the molecule in the form of an amide, R1represents a straight saturated alkyl radical having at least 10 C-atoms and R2represents a straight, saturated alkyl radical having at least 10 C-atoms or a straight alkenyl radical having at least 10 C-atoms and one, two or three double bond(s). Said mixture is characterised in that at least 10 wt. % of the gangliosides of the general formula I are of the group —CO—R1and the acyl-fatty acids are a C20:0 fatty acid. Said mixtures exhibit an improved biological activity.

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