Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving hydrolase
Reexamination Certificate
2006-11-14
2006-11-14
Saidha, Tekchand (Department: 1652)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving hydrolase
C435S219000, C435S069200, C530S412000
Reexamination Certificate
active
07135307
ABSTRACT:
Gamma three protease is provided, a novel aspartyl class protease that is capable of taking part in the processing of amyloid precursor protein (APP) to Aβ peptide. Gamma three protease may be involved in the development and/or progression of Alzheimers disease. Methods of identifying inhibitors of gamma three protease, useful in the prevention or treatment of Alzheimers disease, are disclosed.
REFERENCES:
patent: WO 01/53255 (2001-07-01), None
patent: WO 03/018050 (2002-03-01), None
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Crouthamel Ming-Chih
Gardell Stephen J.
Huang Qian
Lai Ming-Tain
Li Yueming
Giesser Joanne M.
Merck & Co. , Inc.
Saidha Tekchand
Switzer Joan E.
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