Gamma-secretase inhibitors

Details Gamma-secretase inhibitors Gamma-secretase inhibitors

2006-01-10

2006-01-10

Tate, Christopher R. (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S019300, C530S330000, C530S331000, C560S024000, C560S159000

Reexamination Certificate

active

06984626

ABSTRACT:
A class of compounds is disclosed which are diasteroisomers of a known class of protease inhibitors. The compound inhibit gamma-secretase, and find use in the treatment of and/or prevention of Alzheimer's disease.

REFERENCES:
patent: 5703129 (1997-12-01), Felsenstein et al.
patent: 6252041 (2001-06-01), Yanai et al.
patent: 2076204 (1993-02-01), None
patent: 0356223 (1990-02-01), None
patent: WO 94/13319 (1994-06-01), None

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