Gamma-secretase inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S424000, C546S194000, C548S542000

Reexamination Certificate

active

07655675

ABSTRACT:
Compounds of formula I:inhibit the processing of APP by gamma-secretase and hence find use in treatment of Alzheimer's disease.

REFERENCES:
patent: 6890956 (2005-05-01), Churcher et al.
patent: WO 00/50391 (2000-08-01), None
patent: WO 01/70677 (2001-09-01), None
patent: WO 02/081435 (2002-10-01), None
patent: WO 03/018543 (2003-03-01), None
patent: WO 2004/031139 (2004-04-01), None
Cecil Textbook of Medicine, 20th edition (1996), vol. 2, pp. 2050-2057.
Cecil Textbook of Medicine, 20th edition (1996), vol. 2, pp. 1992-1996.
FDA mulls drug to slow late-stage Alzheimer's [online],[retrieved on Sep. 23, 2003].Retrieved from the Internet, URL; http://www.cnn.com/2003/HEALTH/conditions/09/24/alzheimers.drug.ap/indexhtml>.

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