Gamma interferon-interleukin-2 synergism

Details Gamma interferon-interleukin-2 synergism Gamma interferon-interleukin-2 synergism

1990-03-02

1992-01-21

Moskowitz, Margaret

Drug, bio-affecting and body treating compositions

Lymphokine

Interleukin

424 855, 530351, 435 695, 435 6952, A61K 3766, A61K 3702, C07K 1506, C07K 1526

Patent

active

050826581

ABSTRACT:
Compositions containing therapeutically synergistic mixtures of purified gamma interferon and purified interleukin-2 are provided for treatment of tumor-bearing hosts. Preferably, the gamma interferon and interleukin-2 are obtained from recombinant cell synthesis.

REFERENCES:
patent: 4518584 (1985-05-01), Mark et al.
Lotze et al., J. Immunol., vol. 135, pp. 2865-2875, 1985.
Kasahara et al., J. Immunol., vol. 130, pp. 1784-1789, 1983.
Kawase et al, J. Immunol., vol. 131, pp. 288-292, 1983.
Weigent et al., Infection and Immunity, vol. 41, pp. 992-997, 1983.
Handa et al., J. Immunology, vol. 130, pp. 988-992, 1983.
Kuribayashi et al., J. Immunology, vol. 126, pp. 2321-2327, 1981.
Wakasugi et al., JNCI, vol. 69, pp. 807-812, 1982.
Dempsey et al, J. Immunology, vol. 129, pp. 2504-2509, 1982.
Chemical Abstracts, vol. 100, Abstract No. 49809t, 1984.
Chemical Abstracts, vol. 98, Abstract No. 213902f, 1983.
Teh et al., "J. of Immunology", 131(4):1827-1833 (Oct. 1983).
Watson et al., "Lymphokines" 6: Pick et al., ed. 95-115 (1982).
Hefeneider et al., "NK Cells and Other Natural Effector Cells", 421-426 (1982), Herberman ed.
Lattime et al., "J. Exp. Med.", 157:1070-1075 (Mar. 1983).
Henney et al., "Nature", 291:335-338, (28 May 1981).
Toribio et al., "Eur. J. Immunol.", 13:964-969 (1983).
Svedersky et al., "J. of Immunology", 133(2):714-718 (Aug. 1984).

Affiliated with

Also associated with

Rating

Gamma interferon-interleukin-2 synergism does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Gamma interferon-interleukin-2 synergism, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Gamma interferon-interleukin-2 synergism will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-114382